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Fibrous dysplasia is a bone disease that destroys and replaces normal bone with fibrous bone tissue. One or more bones can be affected.

Alternative Names of Fibrous Dysplasia are: Inflammatory fibrous hyperplasia; Idiopathic fibrous hyperplasia.

Complications of Fibrous Dysplasia

  • Cushing's disease
  • Gigantism or acromegaly
  • Heart rhythm disturbance
  • Hyperthyroidism
  • Rickets

Causes of Fibrous Dysplasia

Fibrous dysplasia occurs in childhood, usually between ages 3-15. The condition does not run in families (not hereditary), and the cause is unknown.

Signs & Symptoms of Fibrous Dysplasia

  • Bone pain
  • Bone sores (lesions)
  • Difficulty walking
  • Endocrine gland problems
  • Fractures or bone deformities (rare)
  • Unusual skin color (pigmentation)

The bone lesions may stop when the child reaches puberty.

Diagnosis of Fibrous Dysplasia

The doctor will perform a physical examination. X-rays of bones are taken.

Treatments of Fibrous Dysplasia

There is no cure for fibrous dysplasia. Bone fractures or deformities are treated as appropriate. The patient is screened for endocrine disorders as needed.

Prevention of Fibrous Dysplasia

There is no known way to prevent fibrous dysplasia. Treatment aims to prevent complications, such as recurrent bone fractures, to help make the condition less severe.

When to seek Medical Advice

  • Call your health care provider if your child has symptoms of this condition, such as repeated bone fractures and unexplained bone deformity.
  • Specialists in orthopedics, endocrinology, and genetics may be involved in your child's diagnosis and care.


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