ANKYLOSING SPONDYLITIS (AS) is a form of chronic inflammation of the spine and the sacroiliac joints. Chronic inflammation in these areas causes pain and stiffness in and around the spine. Over time, chronic spinal inflammation can lead to a complete cementing together (fusion) of the vertebrae, a process referred to as ankylosis. Ankylosis leads to loss of mobility of the spine and the condition known as bamboo spine. It is important to note that the course of ankylosing spondylitis varies greatly from person to person. So too can the onset of symptoms. Although symptoms usually start to appear in late adolescence or early adulthood (ages 17-35), the symptoms can occur in children or much later. Typically, the first symptoms of AS are frequent pain and stiffness in the lower back and buttocks, which comes on gradually over the course of a few weeks or months. At first, discomfort may only be felt on one side, or alternate sides. The pain is usually dull and diffuse, rather than localized. This pain and stiffness is usually worse in the mornings and during the night, but may be improved by a warm shower or light exercise. Also, in the early stages of AS, there may be mild fever, loss of appetite and general discomfort. The pain normally becomes persistent (chronic) and is felt on both sides, usually persisting for at least three months. Over the course of months or years, the stiffness and pain can spread up the spine and into the neck. Pain and tenderness spreading to the ribs, shoulder blades, hips, thighs and heels is possible as well. Men are affected more than women by a ratio about of 3:1. AS can also be associated with ulcerative colitis, Crohn's disease, psoriasis, and Reiter's disease. Ayurveda offers excellent therapies for treating Ankylosing spondylitis. The strength of Ayurveda in the area of spine and joint treatments is globally appreciated. Since it addresses the root cause of the issue, the results are fantastic. Ayurveda has in-depth knowledge of causative factors of AS and clearly explained the pathogenesis and line of treatment to be followed. At CHARAKA, we are completely dedicated for treatment of AS. With our deep understanding and research, we are providing a very effective treatment methodology based on the classical texts of Ayurveda. The treatment comprises of Detoxification, rejuvenation through Ayurvedic Panchakarma therapy along with the administration of researched medicines internally. Initial treatment requires around 45 - 60 days of Panchakarma therapy along with internal medicines and diet & life style modification. After this phase only internal medicines are continued. If patient can come for the treatment in early stages, even total cure is also possible.