Depression is a serious medical illness that involves the brain. It is a strong mood involving sadness, discouragement, despair, or hopelessness that lasts for weeks, months, or even longer. Most people with a depressive illness do not seek treatment; although the great majorities even those whose depression is extremely severe can be helped. Unfortunately, many people do not recognize that depression is a treatable illness. The economic cost for this disorder is high, but the cost in human suffering cannot be estimated. Appropriate treatment, however, can help most people who suffer from depression. Depressive illnesses often interfere with normal functioning and cause pain and suffering not only to those who have a disorder, but also to those who care about them. The doctor should ask about alcohol and drug use, and if the patient has thoughts about death or suicide. Our section is aim to provide you comprehensive information on Depression.