Guru is the tale of one manís triumph over his adversities and adversaries to become the most renowned and respected name in the business industry. This man is Gurukant Desai (Abhishek Bachchan), whose life and achievements are broadly based on a great visionary, Dhirubhai Ambani.
Gurukant Desai is a villager with ambitions. His ambitions bring him to Mumbai along with his wife Sujata (Aishwarya Rai) and brother-in-law Shyam Saxena (R. Madhavan).He has only two shirts to wear and Rs.15,000 to start his business. His ambitions get a jolt when he gets negative response from those dealing in the business industry.
During those days the market was ruled by the elite who were veterans and who did not encourage any newcomers especially if that person happened to be from a middle class. Nonetheless Gurukant was a man who would not accept defeat. From here on begins his real struggle to establish himself and break the conventional set up.
With sheer grit to realize his dreams he makes a humble start with his company Shakti Trading. Gurukant adopts an aggressive approach in the wake of tough competition and while doing so he does twist the arms of law at times which in turn earn him some enemies like Nanaji (Mithun Chakraborty ). Nanaji, a newspaper editor was once an admirer of Gurukant but when he realizes his unlawful ways, he turns against him. But at the same time his honesty also earns him admirers like Meenu (Vidya Balan).
Gurukant is riding the waves of success but Nanaji wants to put an end to his unfair means.